{"id":114064,"date":"2020-10-01T08:34:57","date_gmt":"2020-10-01T12:34:57","guid":{"rendered":"https:\/\/www.ucf.edu\/news\/?p=114064"},"modified":"2020-10-01T10:23:49","modified_gmt":"2020-10-01T14:23:49","slug":"optics-and-photonics-researcher-receives-1-7-million-nih-grant","status":"publish","type":"post","link":"https:\/\/www.ucf.edu\/news\/optics-and-photonics-researcher-receives-1-7-million-nih-grant\/","title":{"rendered":"UCF Researcher Receives $1.7 Million NIH Grant"},"content":{"rendered":"<p>Kyu Young Han, an assistant professor in UCF\u2019s <a href=\"https:\/\/creol.ucf.edu\/\">College of Optics and Photonics<\/a>, is the university\u2019s first faculty member to be awarded the National Institutes of Health\u2019s Maximizing Investigators\u2019 Research Award for early stage investigators.<\/p>\n<p>The five-year $1.7 million grant is intended to provide stable funding so recipients can pursue ambitious challenges, according to the National Institute of General Medical Sciences, which oversees the program.<\/p>\n<p>Han, who has a doctorate in chemistry, will use the grant to develop a novel bioengineering tool and imaging system to enable researchers to image multiple proteins in a single cell under a super-resolution microscope. The current technique is extremely slow, taking weeks to months to image fewer than 20 target proteins. Han expects to be able to accomplish this with nanoscale resolution in 24 hours.<\/p>\n<p>If successful, this new tool could be invaluable to researchers trying to understand key biomedical problems from diabetes to cancer because proteins are linked to so many important processes in the body. Specialized proteins play a variety of roles including biochemical reactions, the body\u2019s immune system, scaffolding structures and regulation of metabolisms.<\/p>\n<p>\u201cThat\u2019s why I study optics,\u201d Han says. \u201cMy background, how I got into this, is biophysics and biochemistry. I recognize the potential. It makes sense because we need to know how proteins interact with each other and the surrounding systems. We need to be able to observe those to understand all the connections.\u201d<\/p>\n<p>Han\u2019s work aligns to the goal of the award, which is part of NIH\u2019s Maximizing Investigator Research Awards program.<\/p>\n<p>\u201cThis is my dream job,\u201d he says. \u201cI am excited to get started.\u201d<\/p>\n<figure id=\"attachment_114066\" style=\"max-width: 300px;\" class=\"figure float-left\"><noscript><img decoding=\"async\" width=\"300\" height=\"200\" class=\"figure-img  img-fluid w-100 size-medium wp-image-114066\" src=\"https:\/\/www.ucf.edu\/news\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-300x200.jpg\" alt srcset=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-300x200.jpg 300w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-768x512.jpg 768w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-600x400.jpg 600w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-360x240.jpg 360w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small.jpg 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\"><\/noscript><img decoding=\"async\" width=\"300\" height=\"200\" class=\"figure-img  img-fluid w-100 size-medium wp-image-114066 lazyload\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20300%20200%22%3E%3C%2Fsvg%3E\" alt srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20300%20200%22%3E%3C%2Fsvg%3E 300w\" sizes=\"(max-width: 300px) 100vw, 300px\" data-srcset=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-300x200.jpg 300w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-768x512.jpg 768w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-600x400.jpg 600w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-360x240.jpg 360w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small.jpg 1200w\" data-src=\"https:\/\/www.ucf.edu\/news\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Small-300x200.jpg\"><figcaption class=\"figure-caption\">Kyu Young Han<\/figcaption><\/figure>\n<p>Han said he knew of college\u2019s reputation for optics and photonics, which is why in 2016 he accepted a position at UCF. He has received several grants \u2013 including a National Science Foundation award \u2013 published several journal papers and began training students in this interdisciplinary area of research. Two of his graduate students, Jinhan Ren and Vahid Ebrahimi, will work on the NIH project.<\/p>\n<p>Interdisciplinary ties are critical, he says because of the complexity of the challenge. That\u2019s why for this NIH project he is collaborating with a neuroscientist at Rutgers University and a cell biologist at the University of Illinois.<\/p>\n<p>Before joining UCF, Han worked at the Max Planck Institute in Germany where he studied super-resolution fluorescence imaging. His postdoctoral research, at the University of Illinois at Urbana-Champaign, focused on designing new optical tools for biological applications, such as studying DNA-protein interactions, RNA imaging in live-cells, and revealing nuclear structure in mammalian cells. He has one patent, which was commercialized by Leica<\/p>\n","protected":false},"excerpt":{"rendered":"<p>College of Optics and Photonics Assistant Professor Kyu Young Han will use the funding to develop a new optical technology that could aid in the understanding of human protein linked to diseases.<\/p>\n","protected":false},"author":16,"featured_media":114065,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"lazy_load_responsive_images_disabled":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[5,23,24],"tags":[981,14751,3280,14916],"tu_author":[],"class_list":["post-114064","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colleges","category-research","category-science-technology","tag-college-of-optics-and-photonics","tag-faculty-excellence","tag-nanotechnology","tag-research"],"yoast_head":"<!-- This site is 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Assistant Professor Kyu Young Han will use the funding to develop a new optical technology that could aid in the understanding of human protein linked to diseases.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ucf.edu\/news\/optics-and-photonics-researcher-receives-1-7-million-nih-grant\/\" \/>\n<meta property=\"og:site_name\" content=\"University of Central Florida News | UCF Today\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UCF\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-01T12:34:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-01T14:23:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2020\/10\/WebHan_Full.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" 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