{"id":119284,"date":"2021-04-08T10:50:03","date_gmt":"2021-04-08T14:50:03","guid":{"rendered":"https:\/\/www.ucf.edu\/news\/?p=119284"},"modified":"2025-02-14T13:51:40","modified_gmt":"2025-02-14T18:51:40","slug":"ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction","status":"publish","type":"post","link":"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/","title":{"rendered":"UCF Researcher Studies Alternative Treatment for Depression, Pain and Addiction"},"content":{"rendered":"<p>For many people suffering from depression, chronic pain and addiction, common treatment options such as psychotherapy and medication don\u2019t work, according to scientific and public health reports.<\/p>\n<p>That\u2019s why researchers are exploring alternative methods, such as neural stimulation, in which tiny electrical pulses are sent to a specific brain region to alleviate symptoms of neurological and neuropsychiatric disorders.<\/p>\n<p>In a new study appearing in <em>Nature Biomedical Engineering<\/em>, researchers showed they can predict the effect of these stimulations across multiple brain regions, thus paving the way for personalized treatments.<\/p>\n<p>Electrical neural stimulation, also known as deep brain stimulation, is an established treatment method that uses electrodes implanted in the brain to send therapeutic, electrical impulses that affect brain activity. It is a commonly performed surgical treatment for Parkinson\u2019s disease and has been researched as a treatment for depression, chronic pain and addiction.<\/p>\n<figure id=\"attachment_119293\" style=\"max-width: 200px;\" class=\"figure float-right\"><noscript><img decoding=\"async\" width=\"200\" height=\"300\" class=\"figure-img  img-fluid w-100 size-medium wp-image-119293\" src=\"https:\/\/www.ucf.edu\/news\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-200x300.jpg\" alt=\"Yuxiao Yang\" srcset=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-200x300.jpg 200w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-533x800.jpg 533w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-341x512.jpg 341w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-267x400.jpg 267w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-240x360.jpg 240w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web.jpg 800w\" sizes=\"(max-width: 200px) 100vw, 200px\"><\/noscript><img decoding=\"async\" width=\"200\" height=\"300\" class=\"figure-img  img-fluid w-100 size-medium wp-image-119293 lazyload\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20200%20300%22%3E%3C%2Fsvg%3E\" alt=\"Yuxiao Yang\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20200%20300%22%3E%3C%2Fsvg%3E 200w\" sizes=\"(max-width: 200px) 100vw, 200px\" data-srcset=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-200x300.jpg 200w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-533x800.jpg 533w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-341x512.jpg 341w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-267x400.jpg 267w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-240x360.jpg 240w, https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web.jpg 800w\" data-src=\"https:\/\/www.ucf.edu\/news\/wp-content\/blogs.dir\/20\/files\/2021\/04\/Yuxiao_Yang_for_web-200x300.jpg\"><figcaption class=\"figure-caption\">Yuxiao Yang is the study\u2019s lead author and an assistant professor in UCF\u2019s Department of Electrical and Computer Engineering and a member of UCF\u2019s Disability, Aging and Technology faculty research cluster.<\/figcaption><\/figure>\n<p>However, the understanding of how multi-regional brain activity responds to electrical stimulation has been limited, says the study\u2019s lead author, Yuxiao Yang, an assistant professor in UCF\u2019s Department of Electrical and Computer Engineering and a member of UCF\u2019s <a href=\"https:\/\/www.ucf.edu\/research\/disability-aging-technology\/\">Disability, Aging and Technology<\/a> faculty research cluster.<\/p>\n<p>The researchers worked to overcome this limitation by designing a new electrical stimulation wave that maps brain activity. They also created machine-learning techniques that can track the effects of the stimulations on the pattern of brain activity.<\/p>\n<p>The study is the first to predict multi-regional brain response to ongoing electrical stimulation and will help illuminate ways to improve and understand the effects of neural-stimulation treatments, Yang says.<\/p>\n<p>\u201cOur data-driven approach was able to resolve two standing challenges: first, predicting brain response to ongoing electrical stimulation, and second, doing so for brain activity collected from multiple brain regions,\u201d the researcher says.<\/p>\n<p>\u201cBringing the two features together has implication of developing personalized treatments that automatically adjust the electrical stimulation by the right amount through monitoring the real-time multi-regional brain response,\u201d he says.<\/p>\n<p>The next steps for the researchers will be to further validate their findings.<\/p>\n<p>Study co-authors were Maryam M. Shanechi and Omid G. Sani with the University of Southern California, and Bijan Pesaran, Shaoyu Qiao, J. Isaac Sedillo and Breonna Ferrentino with New York University.<\/p>\n<p>Yang received his doctorate in electrical engineering from the University of Southern California and joined UCF\u2019s Department of Electrical and Computer Engineering, part of UCF\u2019s <a href=\"https:\/\/www.ucf.edu\/college\/engineering-computer-science\/\">College of Engineering and Computer Science<\/a>, in 2020. He also directs the NeuroControl Lab at UCF.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The research paves the way for personalized treatments using neural stimulations of the brain.<\/p>\n","protected":false},"author":199,"featured_media":119292,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"lazy_load_responsive_images_disabled":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[5,23,24],"tags":[973,36305,41782,1516],"tu_author":[],"class_list":["post-119284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colleges","category-research","category-science-technology","tag-college-of-engineering-and-computer-science","tag-department-of-electrical-engineering","tag-disability-aging-technology","tag-electrical-engineering"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v27.1.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>UCF Researcher Studies Alternative Treatment for Depression, Pain and Addiction | University of Central Florida News<\/title>\n<meta name=\"description\" content=\"The research paves the way for personalized treatments using neural stimulations of the brain.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UCF Researcher Studies Alternative Treatment for Depression, Pain and Addiction\" \/>\n<meta property=\"og:description\" content=\"The research paves the way for personalized treatments using neural stimulations of the brain.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/\" \/>\n<meta property=\"og:site_name\" content=\"University of Central Florida News | UCF Today\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UCF\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-08T14:50:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-14T18:51:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/neural_stimulation_for_web.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Robert Wells\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UCF\" \/>\n<meta name=\"twitter:site\" content=\"@UCF\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Robert Wells\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/\"},\"author\":{\"name\":\"Robert Wells\",\"@id\":\"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/9512118dceafb8df4e29be3674361895\"},\"headline\":\"UCF Researcher Studies Alternative Treatment for Depression, Pain and Addiction\",\"datePublished\":\"2021-04-08T14:50:03+00:00\",\"dateModified\":\"2025-02-14T18:51:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/\"},\"wordCount\":459,\"image\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/ucf-researcher-studies-alternative-treatment-for-depression-pain-and-addiction\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2021\/04\/neural_stimulation_for_web.jpg\",\"keywords\":[\"College of Engineering and Computer Science\",\"Department of Electrical Engineering\",\"Disability and Aging Technology\",\"electrical engineering\"],\"articleSection\":[\"Colleges &amp; 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