{"id":3571,"date":"2009-06-18T13:47:22","date_gmt":"2009-06-18T17:47:22","guid":{"rendered":"https:\/\/www.ucf.edu\/news\/?p=3571"},"modified":"2019-07-18T12:43:30","modified_gmt":"2019-07-18T16:43:30","slug":"wake-up-sleepy-gene","status":"publish","type":"post","link":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/","title":{"rendered":"Wake up, Sleepy Gene"},"content":{"rendered":"<p><a href=\"https:\/\/sciences.ucf.edu\/\">UCF scientists<\/a> revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS.<\/p>\n<p>Lead scientist Alexander Cole used drugs commonly used to fight bacterial infections to trigger the production of the sleeping protein.<\/p>\n<p>\u201cIt could make a huge difference in the fight against HIV,\u201d Cole said. \u201cMuch more work would be needed to demonstrate the safety and effectiveness of this approach. We would certainly have to have human trials, but these findings represent a promising step in that direction.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead scientist Alexander Cole used drugs commonly used to fight bacterial infections to trigger the production of the sleeping protein. \u201cIt could make a huge difference in the fight against HIV,\u201d Cole said. \u201cMuch more&hellip;","protected":false},"author":139,"featured_media":3573,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"template-twocol.php","format":"standard","meta":{"_acf_changed":false,"lazy_load_responsive_images_disabled":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[23],"tags":[14914,14916],"tu_author":[],"class_list":["post-3571","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-medicine","tag-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v27.1.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Wake up, Sleepy Gene | University of Central Florida News<\/title>\n<meta name=\"description\" content=\"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Wake up, Sleepy Gene\" \/>\n<meta property=\"og:description\" content=\"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\" \/>\n<meta property=\"og:site_name\" content=\"University of Central Florida News | UCF Today\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UCF\" \/>\n<meta property=\"article:published_time\" content=\"2009-06-18T17:47:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-07-18T16:43:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"450\" \/>\n\t<meta property=\"og:image:height\" content=\"337\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jen Taylor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UCF\" \/>\n<meta name=\"twitter:site\" content=\"@UCF\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jen Taylor\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\"},\"author\":{\"name\":\"Jen Taylor\",\"@id\":\"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf\"},\"headline\":\"Wake up, Sleepy Gene\",\"datePublished\":\"2009-06-18T17:47:22+00:00\",\"dateModified\":\"2019-07-18T16:43:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\"},\"wordCount\":95,\"image\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg\",\"keywords\":[\"Medicine\",\"Research\"],\"articleSection\":[\"Research\"],\"inLanguage\":\"en-US\",\"copyrightYear\":\"2009\",\"copyrightHolder\":{\"@id\":\"https:\/\/www.ucf.edu\/#organization\"}},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\",\"url\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\",\"name\":\"Wake up, Sleepy Gene | University of Central Florida News\",\"isPartOf\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg\",\"datePublished\":\"2009-06-18T17:47:22+00:00\",\"dateModified\":\"2019-07-18T16:43:30+00:00\",\"author\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf\"},\"description\":\"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead\",\"breadcrumb\":{\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage\",\"url\":\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg\",\"contentUrl\":\"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg\",\"width\":450,\"height\":337,\"caption\":\"Professor Alexander Cole Researches HIV Cure\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.ucf.edu\/news\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Wake up, Sleepy Gene\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.ucf.edu\/news\/#website\",\"url\":\"https:\/\/www.ucf.edu\/news\/\",\"name\":\"University of Central Florida News | UCF Today\",\"description\":\"Central Florida Research, Arts, Technology, Student Life and College News, Stories and More\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.ucf.edu\/news\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf\",\"name\":\"Jen Taylor\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/617d43beef5d8ee2d9b176a4fba9d4df12ac59ac1e3843ecd8234364ffc8378b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/617d43beef5d8ee2d9b176a4fba9d4df12ac59ac1e3843ecd8234364ffc8378b?s=96&d=mm&r=g\",\"caption\":\"Jen Taylor\"},\"url\":\"https:\/\/www.ucf.edu\/news\/author\/jtaylor\/\"},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#local-main-organization-logo\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"University of Central Florida\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Wake up, Sleepy Gene | University of Central Florida News","description":"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/","og_locale":"en_US","og_type":"article","og_title":"Wake up, Sleepy Gene","og_description":"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead","og_url":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/","og_site_name":"University of Central Florida News | UCF Today","article_publisher":"https:\/\/www.facebook.com\/UCF","article_published_time":"2009-06-18T17:47:22+00:00","article_modified_time":"2019-07-18T16:43:30+00:00","og_image":[{"width":450,"height":337,"url":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg","type":"image\/jpeg"}],"author":"Jen Taylor","twitter_card":"summary_large_image","twitter_creator":"@UCF","twitter_site":"@UCF","twitter_misc":{"Written by":"Jen Taylor"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#article","isPartOf":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/"},"author":{"name":"Jen Taylor","@id":"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf"},"headline":"Wake up, Sleepy Gene","datePublished":"2009-06-18T17:47:22+00:00","dateModified":"2019-07-18T16:43:30+00:00","mainEntityOfPage":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/"},"wordCount":95,"image":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg","keywords":["Medicine","Research"],"articleSection":["Research"],"inLanguage":"en-US","copyrightYear":"2009","copyrightHolder":{"@id":"https:\/\/www.ucf.edu\/#organization"}},{"@type":"WebPage","@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/","url":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/","name":"Wake up, Sleepy Gene | University of Central Florida News","isPartOf":{"@id":"https:\/\/www.ucf.edu\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage"},"image":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg","datePublished":"2009-06-18T17:47:22+00:00","dateModified":"2019-07-18T16:43:30+00:00","author":{"@id":"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf"},"description":"UCF scientists revived a dormant gene found in humans and coaxed it to produce retrocyclin, a protein that resists HIV, the virus that causes AIDS. Lead","breadcrumb":{"@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#primaryimage","url":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg","contentUrl":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig.jpg","width":450,"height":337,"caption":"Professor Alexander Cole Researches HIV Cure"},{"@type":"BreadcrumbList","@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.ucf.edu\/news\/"},{"@type":"ListItem","position":2,"name":"Wake up, Sleepy Gene"}]},{"@type":"WebSite","@id":"https:\/\/www.ucf.edu\/news\/#website","url":"https:\/\/www.ucf.edu\/news\/","name":"University of Central Florida News | UCF Today","description":"Central Florida Research, Arts, Technology, Student Life and College News, Stories and More","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ucf.edu\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/6c3f4297eed4ecc786d14258bfb0c1cf","name":"Jen Taylor","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.ucf.edu\/news\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/617d43beef5d8ee2d9b176a4fba9d4df12ac59ac1e3843ecd8234364ffc8378b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/617d43beef5d8ee2d9b176a4fba9d4df12ac59ac1e3843ecd8234364ffc8378b?s=96&d=mm&r=g","caption":"Jen Taylor"},"url":"https:\/\/www.ucf.edu\/news\/author\/jtaylor\/"},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.ucf.edu\/news\/wake-up-sleepy-gene\/#local-main-organization-logo","url":"","contentUrl":"","caption":"University of Central Florida"}]}},"thumbnail":"https:\/\/www.ucf.edu\/wp-content\/blogs.dir\/20\/files\/2009\/06\/colestudentsbig-300x225.jpg","primary_category":23,"primary_tag":14914,"author_byline":"Jen Taylor","acf":[],"_links":{"self":[{"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/posts\/3571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/users\/139"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/comments?post=3571"}],"version-history":[{"count":3,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/posts\/3571\/revisions"}],"predecessor-version":[{"id":101004,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/posts\/3571\/revisions\/101004"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/media\/3573"}],"wp:attachment":[{"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/media?parent=3571"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/categories?post=3571"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/tags?post=3571"},{"taxonomy":"tu_author","embeddable":true,"href":"https:\/\/www.ucf.edu\/news\/wp-json\/wp\/v2\/tu_author?post=3571"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}