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Sponsor: National Science Foundation (NSF)

UCF PI: Mehdi Razavi

UCF Co-PIs and Biionix Members: Sudipta Seal, Melanie Coathup

Total Award: $516,762

This grant focuses on enhancing our knowledge and control of nanobubble formation, which are tiny bubbles responsive to ultrasound and capable of releasing their contents upon exposure to sound waves. Although these ultrasound-sensitive nanobubbles show potential for drug delivery and medical imaging, achieving consistent size and distribution during production has been challenging. This project aims to develop a method for generating uniform-sized nanobubbles that can be customized in terms of size and chemical composition as needed.  This innovation could pave the way for production of nanobubbles with diverse applications in biomedicine, including targeted delivery of genes and drugs.

Principal Investigator

Mehdi Razavi, Ph.D.
Assistant Professor of Internal Medicine


Sudipta Seal, Ph.D.
Professor of Materials Science and Engineering
Melanie Coathup, Ph.D.
Professor of Internal Medicine